Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.900 GeneticVariation BEFREE Our findings demonstrate that these variants, which were highly linked with ALDH2 rs671 and ADH1B rs1229984, were significant modulators for AD in our Han Chinese cohort. 31591379 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.900 GeneticVariation BEFREE In the EA GWAS, three loci were genome-wide significant: rs1229984 in ADH1B for AD criterion count (P = 4.16E-11) and Desire to cut drinking (P = 1.21E-11); rs188227250 (chromosome 8, Drinking more than intended, P = 6.72E-09); rs1912461 (chromosome 15, Time spent drinking, P = 1.77E-08). 31090166 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.900 GeneticVariation GWASCAT In the trans-ancestral meta-analysis, rs1229984 was associated with multiple phenotypes and two additional loci were genome-wide significant: rs61826952 (chromosome 1, DSM-IV AD, P = 8.42E-11); rs7597960 (chromosome 2, Time spent drinking, P = 1.22E-08). 31090166 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.900 GeneticVariation BEFREE The inclusion of rs1229984 attenuated the effects of the alcohol consumption PRS, particularly for DSM4AD and DSM5AUDSX, but the PRS continued to exert an independent effect for all 5 alcohol measures (Δmarginal R<sup>2</sup> after controlling for ADH1B = 0.14 to 1.22%). 30994927 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		C 0.900 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
dbSNP: rs1789891
rs1789891
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.820 GeneticVariation BEFREE Recent genome-wide systematic searches found associations between a single nucleotide polymorphism (rs1789891, risk allele: A, protective allele: C) in the alcohol dehydrogenase gene cluster and the risk of alcohol dependence. 29058369 2019
dbSNP: rs2066702
rs2066702
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		G 0.720 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0007222
Disease:
Cardiovascular Diseases 		0.710 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs1154433
rs1154433
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0236664
Disease:
Alcohol-Related Disorders 		G 0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
dbSNP: rs1154433
rs1154433
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0236970
Disease:
Alcohol-Induced Disorders 		G 0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
dbSNP: rs1154433
rs1154433
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		G 0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0236664
Disease:
Alcohol-Related Disorders 		0.700 GeneticVariation GWASCAT Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. 31090166 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0236970
Disease:
Alcohol-Induced Disorders 		C 0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0236970
Disease:
Alcohol-Induced Disorders 		0.700 GeneticVariation GWASCAT Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. 31090166 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0337443
Disease:
Sodium measurement 		T 0.700 GeneticVariation GWASCAT GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits. 31409800 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0236664
Disease:
Alcohol-Related Disorders 		C 0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0005845
Disease:
Blood urea nitrogen measurement 		T 0.700 GeneticVariation GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163 2019
dbSNP: rs1229984
rs1229984
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0871470
Disease:
Systolic Pressure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs1612735
rs1612735
Entrez Id: 125;126
Gene Symbol: ADH1B;ADH1C
ADH1B;ADH1C
CUI: C0236970
Disease:
Alcohol-Induced Disorders 		T 0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
dbSNP: rs1612735
rs1612735
Entrez Id: 125;126
Gene Symbol: ADH1B;ADH1C
ADH1B;ADH1C
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		T 0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
dbSNP: rs1612735
rs1612735
Entrez Id: 125;126
Gene Symbol: ADH1B;ADH1C
ADH1B;ADH1C
CUI: C0236664
Disease:
Alcohol-Related Disorders 		T 0.700 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
dbSNP: rs1789882
rs1789882
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0205682
Disease:
Waist-Hip Ratio 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019